Product Info Summary
SKU: | A01388Y515 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Trk B (phospho-Y515) NTRK2 Antibody
SKU/Catalog Number
A01388Y515
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Trk B (phospho-Y515) NTRK2 Antibody catalog # A01388Y515. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Trk B (phospho-Y515) NTRK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01388Y515)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Emt around the phosphorylation site of Y512.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01388Y515 is reactive to NTRK2 in Human, Mouse, Rat
Applications
A01388Y515 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
91.999kDa
Background of TrkB
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Abujiang Pataer, et,al. (2002) Cancer Res ; 62: 2239.
K. D. Ryman, et,al. (2005) J. Virol ; 79: 1487 - 1499.
Susana Guerra, et,al. (2006) J. Biol. Chem ; 281: 18734 - 18745.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of NTRK2 using Anti-Trk B (phospho-Y515) NTRK2 Antibody (A01388Y515).
Immunohistochemistry (IHC) analyzes of p-Trk B (Y515) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For NTRK2 (Source: Uniprot.org, NCBI)
Gene Name
NTRK2
Full Name
BDNF/NT-3 growth factors receptor
Weight
91.999kDa
Superfamily
protein kinase superfamily
Alternative Names
BDNF/NT-3 growth factors receptor; EC 2.7.10; EC 2.7.10.1; GP145-TrkB; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; NTRK2; TrkB tyrosine kinase; TrkB; trk-B; TRKBBDNF-tropomyosine receptor kinase B; tyrosine kinase receptor B NTRK2 DEE58, EIEE58, GP145-TrkB, OBHD, TRKB, trk-B neurotrophic receptor tyrosine kinase 2 BDNF/NT-3 growth factors receptor|BDNF-tropomyosine receptor kinase B|neurotrophic tyrosine kinase receptor type 2|tropomyosin-related kinase B|tyrosine kinase receptor B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NTRK2, check out the NTRK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NTRK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Trk B (phospho-Y515) NTRK2 Antibody (A01388Y515)
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No publications found for A01388Y515
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